Submitted by Dr Kevin O'Holleran on Tue, 29/09/2015 - 16:49
Müller glia provide essential tensile strength to the developing retina
CAIC's 2-photon microscope was used in the recently published work by MacDonald et. al. to show that Müller glia act like springs in the retina. The Insight DeepSee laser in combination with an electro-opitcal modulator was used to quickly ramp the laser intensity up so that tissue in the focal spot was ablated. This is a very targeted process, only causing tissue in a rugby-ball shaped region, approximately 300nm laterally and 1.5um axially, to be ablated. You can access their findings in the current issue of the Journal of Cell Biology, where an artistic view of the Müller glial cells is shown on the front cover.