The CAIC team attended the 1st annual light sheet fluorescence conference in Barcelona at the end of September. Leila Muresan presented her work on the Double Helix Point Spread Function (DHPSF) in light sheet localisation microscopy and Martin Lenz presented the design of CAIC's light sheet microscope which utilises spatial light modulators and tunable lenses.
The Big Neuron Hackathon starts next week! You can find more information here.
Our new two photon microscope has been installed and is now going through some testing and calibration. It will soon be available for training and booking. There are a few parts yet to be attached to the system but it is functioning well at the moment and we already have some of our first images - more information about the images to follow soon!
CAIC's current SEM will be replaced within the coming months by FEI's Verios 460 XHR SEM with Quorum cryotransfer and EDAX spectrometer. More details to follow.
CAIC's new 2 photon microscope, the TriM Scope II from LaVision BioTec will be installed and running in January 2014. The system will be powered by the Insight DeepSee laser by Spectra Physics (the first installation in the UK). The Insight laser produces a tunable line from 690nm to 1300nm with high power and short pulses across that range. The TriM Scope II will be fitted with adaptive optics, resonant scanner and the most sensitive detectors to allow fast imaging deep into samples whilst reducing photodamage.
The system will be up and running early in 2014.
The CAIC team is growing as we begin to fill the positions funded through the Wellcome Trust that will enable us to fully exploit the light sheet capability we are building. Leila will shortly be joining us from the Centre de Génétique Moléculaire in Gif-sur-Yvette.
As our Scientific Software Engineer her expertise in image processing and data analysis will be crucial in building the infrastructure and algorithms required to fully exploit the capabilities of our light sheet microscopes.